Ovarian Tumors of Low Malignant Potential: Can Molecular Biology Solve This Enigma?

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Ovarian Tumors of Low Malignant Potential

The article by Trimble and Trimble nicely summarizes the state of knowledge on ovarian tumors of low malignant potential (LMP) and underscores the fact that gaps in that knowledge have led to confusion and controversy regarding several issues related to these interesting neoplasms. Many of these controversies can be characterized as debates between the "lumpers" and the "splitters.' The Johns H...

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Ovarian tumors of low malignant potential.

Clinical and laboratory reports suggest that ovarian tumors of low malignant potential (LMP) represent a "grab bag" of tumors, with different etiologies, molecular biologies, and prognoses. As a result, data on incidence and prognosis may be quite unreliable. Diagnosis is best made on permanent section. Half of women under age 40 undergo conservative, fertility-sparing surgery when diagnosed wi...

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Ovarian Tumors of Low Malignant Potential

Executive Summary Ovarian tumors of low malignant potential can be a challenge in daily underwriting, as even clinicians are not in full agreement about the correct approach. This article sheds light on this tumor and highlights some of the key favorable factors when underwriting this condition. INTRODUCTION Ovarian tumors of low malignant potential, also known as borderline tumors of the ovary...

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Commentary (Trimble/Trimble): Update on Low Malignant Potential Ovarian Tumors

Nomenclature Various names have been applied to this entity. These include “ovarian tumors of low malignant potential,” “borderline ovarian tumors,” “atypical proliferating ovarian tumors,” and even “borderline ovarian carcinomas.” Each of these terms has its drawbacks. “Low malignant potential” suggests that these tumors have a certain propensity to become malignant. In fact, as Kurman and Tri...

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Commentary (Seidman/Kurman): Update on Low Malignant Potential Ovarian Tumors

The borderline category of ovarian tumors is one of the most controversial topics in gynecologic oncology and pathology, and is confusing to both clinicians and patients. Although numerous reviews have appeared in the literature, most of them rehash the prevailing views on borderline tumors without critically evaluating the published data that allegedly validate some rather puzzling and perplex...

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ژورنال

عنوان ژورنال: JNCI Journal of the National Cancer Institute

سال: 2001

ISSN: 0027-8874,1460-2105

DOI: 10.1093/jnci/93.15.1122